Found 13 matching trials
A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis PHASE3 The primary objective of this study is to evaluate the effect of brensocati...
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A Phase I Study to Assess PK of AZD7986 Alone & With Verapamil, Itraconazole or Diltiazem in Healthy Subjects PHASE1 This is a phase 1, non-randomized, fixed sequence, 3-period, drug-drug inte...
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A Study to Assess the Relative Bioavailability of Brensocatib Pediatric Oral Solution to Oral Tablets in Healthy Participants PHASE1 The primary purpose of this study is to determine the relative bioavailabil...
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A Study to Investigate Effect of Clarithromycin, a Strong CYP3A4 Inhibitor, on Brensocatib Pharmacokinetics in Healthy Participants PHASE1 The primary purpose of this study is to determine the effect of clarithromy...
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A Study to Assess Pharmacokinetics (PK) of Brensocatib Alone and With Multiple Doses of Rifampin or Esomeprozole in Healthy Participants PHASE1 The primary purpose of this study is to assess the effects of rifampin on t...
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A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) PHASE2 The primary purpose of the study is to evaluate the efficacy of brensocatib...
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A Study of the Safety, Pharmacokinetics, and Pharmacodynamics of INS1007 in Healthy Japanese and Caucasian Participants PHASE1 The primary purpose of Part A of this study is to compare, in a single dose...
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A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS) PHASE2 The primary purpose of the study is to evaluate the effect of brensocatib c...
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A Study of Brensocatib Following a Single Oral Administration in Participants With or Without Renal Impairment PHASE1 The primary purpose of the study is to determine the pharmacokinetics (PK) ...
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A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Brensocatib in Participants With Normal Hepatic Function and Participants With Hepatic Impairment PHASE1 The primary purpose of the study is to compare the PK of a single dose of b...
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